TY - JOUR
T1 - Gradients of HLA diversity in South American Indians
AU - Rothhammer, F.
AU - Silva, C.
AU - Callegari-Jacques, S. M.
AU - Llop, E.
AU - Salzano, F. M.
PY - 1997
Y1 - 1997
N2 - Information concerning the HLA-A and -B loci was considered in relation to 3796 Amerindians living in 39 places in South America, data related to HLA-C being based on a smaller subset of 2989 persons distributed among 33 localities. Synthetic gene frequency maps were then constructed using principal-components analysis. Clearly significant longitudinal (principal component 1) and latitudinal (principal components 1, 2, and 3) clines were observed, most probably indicating ancient migration routes.
AB - Information concerning the HLA-A and -B loci was considered in relation to 3796 Amerindians living in 39 places in South America, data related to HLA-C being based on a smaller subset of 2989 persons distributed among 33 localities. Synthetic gene frequency maps were then constructed using principal-components analysis. Clearly significant longitudinal (principal component 1) and latitudinal (principal components 1, 2, and 3) clines were observed, most probably indicating ancient migration routes.
UR - https://www.scopus.com/pages/publications/0031135544
U2 - 10.1080/03014469700004932
DO - 10.1080/03014469700004932
M3 - Article
C2 - 9158839
AN - SCOPUS:0031135544
SN - 0301-4460
VL - 24
SP - 197
EP - 208
JO - Annals of Human Biology
JF - Annals of Human Biology
IS - 3
ER -