Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd; Francisco Rothhammer; Yedy Israel

doi:10.1111/j.1530-0277.1990.tb01194.x

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd
, Francisco Rothhammer
, Yedy Israel

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

29 Citas (Scopus)

Resumen

Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH2²) allele frequently found in Orientals.

Idioma original	Inglés
Páginas (desde-hasta)	531-533
Número de páginas	3
Publicación	Alcoholism: Clinical and Experimental Research
Volumen	14
N.º	4
DOI	https://doi.org/10.1111/j.1530-0277.1990.tb01194.x
Estado	Publicada - ago. 1990
Publicado de forma externa	Sí

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title = "Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians",

abstract = "Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.",

keywords = "Aldehyde Dehydrogenase, American Indian, Genotyping, Hair Root, Polymerase Chain Reaction",

author = "O'Dowd, \{Brian F.\} and Francisco Rothhammer and Yedy Israel",

year = "1990",

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doi = "10.1111/j.1530-0277.1990.tb01194.x",

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journal = "Alcoholism: Clinical and Experimental Research",

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AU - O'Dowd, Brian F.

AU - Rothhammer, Francisco

AU - Israel, Yedy

PY - 1990/8

Y1 - 1990/8

N2 - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

AB - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

KW - Aldehyde Dehydrogenase

KW - American Indian

KW - Genotyping

KW - Hair Root

KW - Polymerase Chain Reaction

UR - https://www.scopus.com/pages/publications/0025127809

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DO - 10.1111/j.1530-0277.1990.tb01194.x

M3 - Article

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AN - SCOPUS:0025127809

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JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

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ER -

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

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