Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd; Francisco Rothhammer; Yedy Israel

doi:10.1111/j.1530-0277.1990.tb01194.x

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd
, Francisco Rothhammer
, Yedy Israel

University of Toronto
Universidad de Chile

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

29 Citas (Scopus)

Resumen

Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH2²) allele frequently found in Orientals.

Idioma original	Inglés
Páginas (desde-hasta)	531-533
Número de páginas	3
Publicación	Alcoholism: Clinical and Experimental Research
Volumen	14
N.º	4
DOI	https://doi.org/10.1111/j.1530-0277.1990.tb01194.x
Estado	Publicada - ago 1990
Publicado de forma externa	Sí

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar

Acceder al documento

10.1111/j.1530-0277.1990.tb01194.x

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

@article{9dd256c64d2a4d10bd6eabd8ee4fde9d,

title = "Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians",

abstract = "Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.",

keywords = "Aldehyde Dehydrogenase, American Indian, Genotyping, Hair Root, Polymerase Chain Reaction",

author = "O'Dowd, \{Brian F.\} and Francisco Rothhammer and Yedy Israel",

year = "1990",

month = aug,

doi = "10.1111/j.1530-0277.1990.tb01194.x",

language = "English",

volume = "14",

pages = "531--533",

journal = "Alcoholism: Clinical and Experimental Research",

issn = "0145-6008",

publisher = "Wiley",

number = "4",

}

TY - JOUR

T1 - Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

AU - O'Dowd, Brian F.

AU - Rothhammer, Francisco

AU - Israel, Yedy

PY - 1990/8

Y1 - 1990/8

N2 - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

AB - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

KW - Aldehyde Dehydrogenase

KW - American Indian

KW - Genotyping

KW - Hair Root

KW - Polymerase Chain Reaction

UR - https://www.scopus.com/pages/publications/0025127809

U2 - 10.1111/j.1530-0277.1990.tb01194.x

DO - 10.1111/j.1530-0277.1990.tb01194.x

M3 - Article

C2 - 2221278

AN - SCOPUS:0025127809

SN - 0145-6008

VL - 14

SP - 531

EP - 533

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

IS - 4

ER -

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto