TY - JOUR
T1 - DNA-based prediction of eye color in Latin American population applying Machine Learning models
AU - Martínez, Cristian A.
AU - Hohl, Diana M.
AU - Gutiérrez, María de los A.
AU - Palmal, Sagnik
AU - Faux, Pierre
AU - Adhikari, Kaustubh
AU - Gonzalez-Jose, Rolando
AU - Bortolini, Maria C.
AU - Acuña-Alonzo, Victor
AU - Gallo, Carla
AU - Linares, Andres Ruiz
AU - Rothhammer, Francisco
AU - Catanesi, Cecilia I.
AU - Barrientos, Ricardo J.
N1 - Publisher Copyright:
© 2025 Elsevier Ltd
PY - 2025/8
Y1 - 2025/8
N2 - Reduction in the costs of DNA sequencing and genotyping allows for the increased availability of databases which can be useful for analyzing the relationship between the human genetic code and visible characteristics, diseases, and behaviors, among others. The aim of this study is to improve the prediction of eye color from genotype by means of several Machine Learning models, using a dataset of 308 volunteers from Buenos Aires, Argentina. The results achieved are competitive and demonstrate the usefulness of artificial intelligence (AI) in the fields of genetics and its application in areas such as health, biometrics and forensics.
AB - Reduction in the costs of DNA sequencing and genotyping allows for the increased availability of databases which can be useful for analyzing the relationship between the human genetic code and visible characteristics, diseases, and behaviors, among others. The aim of this study is to improve the prediction of eye color from genotype by means of several Machine Learning models, using a dataset of 308 volunteers from Buenos Aires, Argentina. The results achieved are competitive and demonstrate the usefulness of artificial intelligence (AI) in the fields of genetics and its application in areas such as health, biometrics and forensics.
KW - DNA phenotyping
KW - Eye color prediction
KW - Forensic DNA
KW - Machine Learning
UR - https://www.scopus.com/pages/publications/105007598452
U2 - 10.1016/j.compbiomed.2025.110404
DO - 10.1016/j.compbiomed.2025.110404
M3 - Article
AN - SCOPUS:105007598452
SN - 0010-4825
VL - 194
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
M1 - 110404
ER -
