TY - JOUR
T1 - Dental size variation in admixed Latin Americans
T2 - Effects of age, sex and genomic ancestry
AU - Yang, Guangrui
AU - Chen, Yingjie
AU - Li, Qing
AU - Benítez, Daniel
AU - Ramírez, Luis Miguel
AU - Fuentes-Guajardo, Macarena
AU - Hanihara, Tsunehiko
AU - Scott, G. Richard
AU - Alonzo, Victor Acuña
AU - Jose, Rolando Gonzalez
AU - Bortolini, Maria Catira
AU - Poletti, Giovanni
AU - Gallo, Carla
AU - Rothhammer, Francisco
AU - Rojas, Winston
AU - Zanolli, Clément
AU - Adhikari, Kaustubh
AU - Ruiz-Linares, Andres
AU - Delgado, Miguel
N1 - Publisher Copyright:
© 2023 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2023/5
Y1 - 2023/5
N2 - Dental size variation in modern humans has been assessed from regional to worldwide scales, especially under microevolutionary and forensic contexts. Despite this, populations of mixed continental ancestry such as contemporary Latin Americans remain unexplored. In the present study we investigated a large Latin American sample from Colombia (N = 804) and obtained buccolingual and mesiodistal diameters and three indices for maxillary and mandibular teeth (except third molars). We evaluated the correlation between 28 dental measurements (and three indices) with age, sex and genomic ancestry (estimated using genome-wide SNP data). In addition, we explored correlation patterns between dental measurements and the biological affinities, based on these measurements, between two Latin American samples (Colombians and Mexicans) and three putative parental populations: Central and South Native Americans, western Europeans and western Africans through PCA and DFA. Our results indicate that Latin Americans have high dental size diversity, overlapping the variation exhibited by the parental populations. Several dental dimensions and indices have significant correlations with sex and age. Western Europeans presented closer biological affinities with Colombians, and the European genomic ancestry exhibited the highest correlations with tooth size. Correlations between tooth measurements reveal distinct dental modules, as well as a higher integration of postcanine dentition. The effects on dental size of age, sex and genomic ancestry is of relevance for forensic, biohistorical and microevolutionary studies in Latin Americans.
AB - Dental size variation in modern humans has been assessed from regional to worldwide scales, especially under microevolutionary and forensic contexts. Despite this, populations of mixed continental ancestry such as contemporary Latin Americans remain unexplored. In the present study we investigated a large Latin American sample from Colombia (N = 804) and obtained buccolingual and mesiodistal diameters and three indices for maxillary and mandibular teeth (except third molars). We evaluated the correlation between 28 dental measurements (and three indices) with age, sex and genomic ancestry (estimated using genome-wide SNP data). In addition, we explored correlation patterns between dental measurements and the biological affinities, based on these measurements, between two Latin American samples (Colombians and Mexicans) and three putative parental populations: Central and South Native Americans, western Europeans and western Africans through PCA and DFA. Our results indicate that Latin Americans have high dental size diversity, overlapping the variation exhibited by the parental populations. Several dental dimensions and indices have significant correlations with sex and age. Western Europeans presented closer biological affinities with Colombians, and the European genomic ancestry exhibited the highest correlations with tooth size. Correlations between tooth measurements reveal distinct dental modules, as well as a higher integration of postcanine dentition. The effects on dental size of age, sex and genomic ancestry is of relevance for forensic, biohistorical and microevolutionary studies in Latin Americans.
UR - https://www.scopus.com/pages/publications/85159094262
U2 - 10.1371/journal.pone.0285264
DO - 10.1371/journal.pone.0285264
M3 - Article
C2 - 37141293
AN - SCOPUS:85159094262
SN - 1932-6203
VL - 18
JO - PLoS ONE
JF - PLoS ONE
IS - 5 May
M1 - e0285264
ER -