Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd; Francisco Rothhammer; Yedy Israel

doi:10.1111/j.1530-0277.1990.tb01194.x

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Brian F. O'Dowd
, Francisco Rothhammer
, Yedy Israel

University of Toronto
Universidad de Chile

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH2²) allele frequently found in Orientals.

Original language	English
Pages (from-to)	531-533
Number of pages	3
Journal	Alcoholism: Clinical and Experimental Research
Volume	14
Issue number	4
DOIs	https://doi.org/10.1111/j.1530-0277.1990.tb01194.x
State	Published - Aug 1990
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Aldehyde Dehydrogenase
American Indian
Genotyping
Hair Root
Polymerase Chain Reaction

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10.1111/j.1530-0277.1990.tb01194.x

Cite this

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title = "Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians",

abstract = "Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.",

keywords = "Aldehyde Dehydrogenase, American Indian, Genotyping, Hair Root, Polymerase Chain Reaction",

author = "O'Dowd, \{Brian F.\} and Francisco Rothhammer and Yedy Israel",

year = "1990",

month = aug,

doi = "10.1111/j.1530-0277.1990.tb01194.x",

language = "English",

volume = "14",

pages = "531--533",

journal = "Alcoholism: Clinical and Experimental Research",

issn = "0145-6008",

publisher = "Wiley",

number = "4",

}

TY - JOUR

T1 - Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

AU - O'Dowd, Brian F.

AU - Rothhammer, Francisco

AU - Israel, Yedy

PY - 1990/8

Y1 - 1990/8

N2 - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

AB - Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals.

KW - Aldehyde Dehydrogenase

KW - American Indian

KW - Genotyping

KW - Hair Root

KW - Polymerase Chain Reaction

UR - https://www.scopus.com/pages/publications/0025127809

U2 - 10.1111/j.1530-0277.1990.tb01194.x

DO - 10.1111/j.1530-0277.1990.tb01194.x

M3 - Article

C2 - 2221278

AN - SCOPUS:0025127809

SN - 0145-6008

VL - 14

SP - 531

EP - 533

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

IS - 4

ER -

Genotyping of Mitochondrial Aldehyde Dehydrogenase Locus of Native American Indians

Abstract

UN SDGs

Keywords

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