Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas’ Perspective

Alejandra Alarcón; Ursula Figueroa; Bastian Espinoza; Alejandra Sandoval; Gonzalo Carrasco-Aviño; Francisco R. Aguayo; Alejandro H. Corvalan

doi:10.5772/intechopen.70201

Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas’ Perspective

Translated title of the contribution: Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas’ Perspective

Alejandra Alarcón
, Ursula Figueroa
, Bastian Espinoza
, Alejandra Sandoval
, Gonzalo Carrasco-Aviño
, Francisco R. Aguayo
, Alejandro H. Corvalan

Pontificia Universidad Católica de Chile
Universidad de Chile

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Epstein-Barr virus (EBV) infection has been associated with different malignancies, and compelling evidence has shown that it may have a causative or at least contributing role in gastric carcinogenesis. EBV-associated gastric cancers have a unique molecular signature, which has defined this group of tumors as a distinctive molecular subtype of gastric cancer. This subtype has shown a greater incidence in the Americas than in the Asian countries. This chapter discusses about possible factors underlying these differences and the emerging roles of epigenetics in the pathogenesis of Epstein-Barr virus–associated gastric cancer.

Translated title of the contribution	Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas’ Perspective
Original language	English
Title of host publication	Gastric Cancer
Editors	Gyula Mozsik, Oszkár Karádi
Publisher	IntechOpen
Chapter	2
ISBN (Electronic)	978-953-51-3528-9, 978-953-51-4645-2
ISBN (Print)	978-953-51-3527-2
DOIs	https://doi.org/10.5772/intechopen.70201
State	Published - 20 Sep 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Gastric cancer
Epstein-Barr virus
Strains
Phylogeographic diversity
Epigenetic abnormalities

Access to Document

10.5772/intechopen.70201License: CC BY

Cite this

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title = "Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas{\textquoteright} Perspective",

abstract = "Epstein-Barr virus (EBV) infection has been associated with different malignancies, and compelling evidence has shown that it may have a causative or at least contributing role in gastric carcinogenesis. EBV-associated gastric cancers have a unique molecular signature, which has defined this group of tumors as a distinctive molecular subtype of gastric cancer. This subtype has shown a greater incidence in the Americas than in the Asian countries. This chapter discusses about possible factors underlying these differences and the emerging roles of epigenetics in the pathogenesis of Epstein-Barr virus–associated gastric cancer.",

keywords = "C{\'a}ncer g{\'a}strico, Virus de Epstein-Barr, Cepas, Diversidad filogeogr{\'a}fica, Anomal{\'i}as epigen{\'e}ticas, Gastric cancer, Epstein-Barr virus, Strains, Phylogeographic diversity, Epigenetic abnormalities",

author = "Alejandra Alarc{\'o}n and Ursula Figueroa and Bastian Espinoza and Alejandra Sandoval and Gonzalo Carrasco-Avi{\~n}o and Aguayo, \{Francisco R.\} and Corvalan, \{Alejandro H.\}",

year = "2017",

month = sep,

day = "20",

doi = "10.5772/intechopen.70201",

language = "English",

isbn = "978-953-51-3527-2",

editor = "Gyula Mozsik and Oszk{\'a}r Kar{\'a}di",

booktitle = "Gastric Cancer",

publisher = "IntechOpen",

address = "United Kingdom",

}

TY - CHAP

T1 - Epstein-Barr Virus–Associated Gastric Carcinoma

T2 - The Americas’ Perspective

AU - Alarcón, Alejandra

AU - Figueroa, Ursula

AU - Espinoza, Bastian

AU - Sandoval, Alejandra

AU - Carrasco-Aviño, Gonzalo

AU - Aguayo, Francisco R.

AU - Corvalan, Alejandro H.

PY - 2017/9/20

Y1 - 2017/9/20

N2 - Epstein-Barr virus (EBV) infection has been associated with different malignancies, and compelling evidence has shown that it may have a causative or at least contributing role in gastric carcinogenesis. EBV-associated gastric cancers have a unique molecular signature, which has defined this group of tumors as a distinctive molecular subtype of gastric cancer. This subtype has shown a greater incidence in the Americas than in the Asian countries. This chapter discusses about possible factors underlying these differences and the emerging roles of epigenetics in the pathogenesis of Epstein-Barr virus–associated gastric cancer.

AB - Epstein-Barr virus (EBV) infection has been associated with different malignancies, and compelling evidence has shown that it may have a causative or at least contributing role in gastric carcinogenesis. EBV-associated gastric cancers have a unique molecular signature, which has defined this group of tumors as a distinctive molecular subtype of gastric cancer. This subtype has shown a greater incidence in the Americas than in the Asian countries. This chapter discusses about possible factors underlying these differences and the emerging roles of epigenetics in the pathogenesis of Epstein-Barr virus–associated gastric cancer.

KW - Cáncer gástrico

KW - Virus de Epstein-Barr

KW - Cepas

KW - Diversidad filogeográfica

KW - Anomalías epigenéticas

KW - Gastric cancer

KW - Epstein-Barr virus

KW - Strains

KW - Phylogeographic diversity

KW - Epigenetic abnormalities

U2 - 10.5772/intechopen.70201

DO - 10.5772/intechopen.70201

M3 - Chapter

SN - 978-953-51-3527-2

BT - Gastric Cancer

A2 - Mozsik, Gyula

A2 - Karádi, Oszkár

PB - IntechOpen

ER -

Epstein-Barr Virus–Associated Gastric Carcinoma: The Americas’ Perspective

Abstract

UN SDGs

Keywords

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